Addressing exaggeration of effects from single RCTs

RCTs are often presented as the gold standard for testing new treatments. But in early stages of research, reports from single trials are likely to show exaggerated effect estimates. @ErikVanZwet, @SimonSchw4b & @Lester_Domes explain why & propose a remedy https://t.co/Sz7gBYVLyK pic.twitter.com/bpTdQ7iNNu

— Significance (@signmagazine) December 14, 2021